14-3-3 proteins interact with a wide spectrum of proteins and possess diverse functions. Mammals express seven distinct 14-3-3 isoforms (gamma, epsilon, beta, zeta, sigma, theta, tau) that form multiple homo- and hetero- dimmers. 14-3-3 proteins display the highest expression levels in the brain, and have been implicated in several neurodegenerative diseases, including Alzheimer's disease and amyotrophic lateral sclerosis. 66061-1-Ig recognizes 14-3-3 tau (YWHAQ), eta (YWHAH), and zeta (YWHAZ), but not epsilon (YWHAE).
Source: | Isotype: |
Mouse | IgG1 |
Purification method: | Storage: |
Protein G purification | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20℃. Aliquoting is unnecessary for -20℃ storage. |
仅限科研用。
培养体系中的一些组分是对人体健康有害的物质，请不要用暴露的皮肤接触培养体系的液体和有培养体系的液体残留的容器内部；这部分有害物质的浓度和危害性都较低，如有接触，立即用自来水冲洗即可。
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